In which stage of HIV is a client with a CD4+ T-cell count of 325 cells/mm3 classified?

A client with a CD4+ T-cell count of 325 cells/mm3 is classified in Stage 2 of HIV infection. The classification of HIV stages is based on the CD4+ T-cell count as well as the presence of any opportunistic infections.

In the context of HIV, the stages are defined as follows:

• Stage 1 is characterized by a CD4+ count of 500 cells/mm3 or more, indicating a relatively high level of immune function.

• Stage 2 includes CD4+ counts from 200 to 499 cells/mm3. This range represents a moderate decline in immune function, which is where a count of 325 cells/mm3 falls.

• Stage 3 is classified as AIDS (Acquired Immunodeficiency Syndrome), which includes a CD4+ count of less than 200 cells/mm3 or the presence of certain opportunistic infections regardless of CD4+ count.

• Stage 4 is used for more severe manifestations of the disease and also includes patients with a CD4+ count lower than 200 cells/mm3.

Therefore, a count of 325 cells/mm3 indicates that the client's immune system is still moderately functional and supports the classification of Stage 2 for this stage of HIV infection.